As the active ingredient in this drug is used Metamizole sodium, which prevents the passage of pain impulses to the brain. Analgin also increases the body's heat and reduces the excitability of the centers of pain sensitivity in the human body.
Analgin has a slight anti-inflammatory effect. Thus, the drug minimally affects the activity of the gastrointestinal tract and retains water and salt balance. The drug has antipyretic effects. Tablets have antispasmodic effect, which occurs about 30 minutes after taking the drug.
As antipyretic Analgin shows greater efficacy than an Aspirin, "Ibuprofen" and "Paracetamol".
"Analgin" can be assigned for fevers, mild and moderate pain syndromes (neuralgia, arthralgia, intestinal colic, etc.). "Analgin" is widely used to relieve postoperative, head and dental pain until a more secure means of anesthesia and analgesia.
At the moment Analgin is banned drug in most Western countries because of the increased risk of agranulocytosis, which in 7% of cases can lead to death.
In contrast to the "Analginum" "Tsitramon" is composed of acetylsalicylic acid, caffeine and paracetamol, what is the difference between the drugs. Each of the substances included in the composition, has a different effect, due to which the drug received its initial distribution.
Acetylsalicylic acid (aspirin) has antipyretic effect, which may be initiated by the inflammatory process. Aspirin relieves pain, improves circulation and reduces blood clotting. Caffeine helps the brain by dilating blood vessels and improving blood flow, easing pain and eliminating drowsiness. Caffeine also stimulates physical and mental activity. Paracetamol has antipyretic action and is able to act as a painkiller.
Despite its efficiency, "Citramon" has a large number of contraindications, ranging from hives, asthma or acute rhinitis, to the increased excitability and sleep disorders.
The drug is indicated for pain syndromes of different severity, fevers, acute respiratory infections and influenza. As "Analginum" "Tsitramon" is rarely used in Western countries because of its negative impact on internal organs, especially the liver.