The main property of glycerol is the ability to provide on the mucous membrane of the rectum, local irritating action. It stimulates peristalsis, causing its natural evacuation. In addition, the components included in the suppository, have a high hygroscopicity. They attract to themselves fluid, softening the stool and greatly easing the process of defecation.
Usually, the glycerin suppository start to work pretty quickly, within 15-20 minutes after injection. It should be remembered that the constant use of this drug is undesirable. The regular irritation of receptors of the intestine can provoke a loss of sensitivity, then the problem of constipation is worse.
Glycerin suppository is contraindicated in the acute stage of hemorrhoids, fissures in the anus, inflammation and tumours in the rectum. With great care this drug is used in the first and last trimester of pregnancy, because glycerin contributes to the relaxation of smooth muscles of the uterus, near the bowel. It can cause miscarriage or premature birth. Need expert advice.