One of the features of this hormone is its unstable concentration in the blood women amount of progesterone depends directly on the phases of the cycle, pregnancy and its term. Indicators of progesterone are extremely important for the diagnosis of infertility, lack of milk, miscarriages, abnormalities of fetal development and disorders in the reproductive system. Tests for hormone levels usually pass on different days of the menstrual cycle – thus it is necessary to properly prepare for this procedure.
Before taking progesteronethe analysis can not be there – last time, it is desirable to eat 12 hours before blood sampling. This day should be excluded from the diet of fried or fatty foods, alcohol and physical activity. You can drink only pure water. Also be sure to inform your doctor about medications or birth control pills that can increase or reduce the concentration of progesterone in the blood. Upon detection of deviations in normal parameters, the physician may prescribe an ultrasound of the pelvic organs and the levels of several other hormones.
On different days of the menstrual cycle the progesterone level is significantly different. So, in the follicular phase (first day of menstruation and for the next two weeks) his rule shall be from 0.31 to 2.23 nmol/l In ovulatory phase (14th day of the cycle), the level of the hormone increases to 0.48-9.41 nmol/l In luteal phase (15-28 days) its concentration reaches its peak and ranges from 6.99 to 56.63 nmol/L.
The first trimester of pregnancy is characterized by normal progesterone from 468.4 to 8.9 nmol/l, whereas in the second trimester of his figure is already from 71 to 303.1 nmol/l In the third trimester, the progesterone level reaches 88.7-771.5 nmol/l and falls before the birth, staying after the baby is born. Low concentration of this hormone can talk about the threat of infertility or miscarriage, therefore, in such cases the woman increase his level by medication. High concentrations of progesterone are characteristic not only for pregnancy, but also for the cyst of the corpus luteum of the ovary, tumor, pathological overgrowth of the placenta, adrenal tumors or renal failure.
Pregnant women often submit to a blood progesterone on day 19-21 of the cycle, but your doctor may prescribe another period, based on beginning and end of last period.
Next month all is repeated again - the level of progesterone begins to decline at the onset of the follicular phase and grow into ovulatory and luteal.