Lidocaine and novocaine. What is best pain reliever?
To determine which of the funds, procaine or lidocaine, stronger pain medication, you need to understand the concepts. Called lidocaine is a potent local anesthetic, which is used for local anesthesia in dentistry, ophthalmology, and otolaryngology. The effect of anesthesia, this means much higher than that of novocaine. The lidocaine used for local anesthesia. This substance is highly toxic. So doctors use in their profession this drug very carefully. Novocaine is a drug with a moderate anaesthetic activity. It is used in medicine for local anesthesia. But unlike lidocaine, the effect of the novocaine wears short character. Often Novocain used in dentistry, urology and surgery. After absorption into the blood novocaine has anti-inflammatory, energeziruyuschim, antitoxic effect. Novocaine relieves spasms of smooth muscles and reduces tension of the muscles of the heart.
Difference between lidocaine and novocaine
Lidocaine and novocaine are very similar in chemical structure. Both substances are used for local anesthesia. Both groups of local anesthetics (Aida and esters) consist of hydrophobic aromatic groups, ether or amide intermediate chain, hydrophilic secondary or tertiary amino group. Type intermediate circuit has an impact on the duration of action of the drug. Because the drugs are divided according to the use of esters and amides. Novocaine is a group of esters, and lidocaine in a group of amides. Here and take the differences. Esters are unstable in solution and rapidly hydrolyzed when injected into the body (decomposition of the original substances under the action of water). The hydrolysis products may cause allergic reactions in humans. The same amides are relatively stable and break down slowly. Allergic reaction to amides is much less. A small part of the anesthetics, even if it is just lidocaine, novocaine, though, is excreted in the urine. Everything else is broken down in the body and excreted out. Doctor-specialist must correctly calculate the dosage of anesthetic. In case of overdose a person may experience seizures, apnea, and sometimes even coma.
General conclusions
Lidocaine is an effective local anesthetic application. Novocaine is a drug with a moderate anaesthetic activity. Lidocaine belongs to the group of amides, Novocain – to the group of esters. Lidocain belongs to the category of highly toxic drugs. Novocain is less toxic.