Advice 1: "Omeprazole": indications, contraindications and side effects

The drug "Omeprazole" is intended for the treatment of peptic ulcer disease. This drug lowers the acidity of gastric juice, regulates motor function of the gastrointestinal tract, promotes scarring ulcers.
The Drug "Omeprazole"

Indications for use


"Omeprazole" is used for the treatment of peptic ulcer disease in different manifestations. In particular, a drug used for the treatment of stomach ulcers, duodenal ulcers, peptic ulcers caused by Helicobacterpylori, reflux esophagitis. The drug is also prescribed for benign tumors of the pancreas in combination with gastric ulcer (syndrome zollingerellison).
The drug "Omeprazole" is available in capsule form at a dosage of 10, 20 and 40 mg.


Instructions for use of "Omeprazole"


Peptic ulcer disease is prescribed 20 mg "Omeprazole" 1 time daily, in the morning, a course of 2 weeks. Sometimes the duration of treatment was increased to 4 weeks. In case of poor saeplast ulcers dosage is 40 mg "Omeprazole" course in 8 weeks. For the prevention administered 10-40 mg 1 times a day. Maintenance dosage depends on the severity of the disease.

When reflux esophagitis daily dose is 20 mg "Omeprazole", the course of treatment lasts 4 weeks; in severe cases, take 40 mg of the drug in the course of 8 weeks. In the treatment of peptic ulcer appoint 20-40 mg of the drug "Omeprazole" twice a day for 2-4 weeks. The syndrome of zollingerellison determine the dose of 60 mg "Omeprazole" 1 times a day, in severe cases, 40 to 60 mg 2 times a day.
"Omeprazole" before taking food.


Contraindications and cautions


"Omeprazole" do not take if you are allergic to its components. The drug is not prescribed to persons with chronic liver disease, including history. Treatment by this means is contraindicated in children, during pregnancy and lactation.

Before therapy data drug need to exclude the presence of malignant tumors in a patient, since taking "Omeprazole" may mask the symptoms of the disease and delay, thus its timely diagnosis.

Side effects


As a rule, the treatment of "Omeprazole" is well tolerated. Occasionally during treatment there can be side effects such as muscle weakness, joint pain, dizziness, drowsiness, headache, sleep disturbances, dry mouth, nausea, stool disorders, stomach pain, flatulence, gastrointestinal candidiasis. From the hematopoietic system possible neutropenia, thrombocytopenia and anemia. Sometimes there are allergic reactions in the form of bronchospasm, rash, itching, hives and increased sweating. If you experience side effects of the drug are required.

Advice 2 : "Omeprazole": indications for use and duration of treatment

"Omeprazole" is a synthetic anti-ulcer drug that is prescribed to reduce the secretion of gastric juice. It exerts its effect regardless of the type of stimulus.
"Omeprazole": indications for use and duration of treatment

Indications and duration of treatment "Omeprazole"



The drug "Omeprazole" is prescribed for the treatment and prevention of ulcers stomach and duodenal ulcers, reflux esophagitis (inflammation of the lining of the esophagus caused by reflux of stomach contents into the esophagus), when gipersecrethornykh States of stress ulcers of the gastrointestinal tract, polyendocrine adenomatosis, systemic mastocytosis, syndrome zollingerellison. Also it is used in General anaesthesia to prevent regurgitation of stomach contents into the respiratory tract. The equivalent of "Omeprazole" are: "Omez", "Losec", "Mcaps", "Acid", "Pepticum", etc.

"Omeprazole" need to be taken once a day (in the morning), regardless of the meal. Capsules cannot be chewed, they are swallowed whole and washed down with a small amount of water. In the case of aggravation of peptic ulcer disease, with reflux-ezofagite appoint on 20 mg "Omeprazole" 1 times a day. Patients with severe reflux esophagitis, it is necessary to take 40 mg of the drug. When the sore, as the syndrome zollingerellison (tumor islet apparatus of the pancreas) "Omeprazole" is prescribed at a dose of 60 mg per day. This number if necessary increase to 80-120 mg per day, in this case this dose should be divided into two or three doses. For the prevention of exacerbations of peptic ulcer disease patients need to take 10 mg once a day. The drug is effective in chronic pancreatitis, it is taken for elimination of pain syndrome.
In the case of impaired renal function and in elderly adjustment of the dosing regimen is not carried out.


Treated "with Omeprazole" ulcer 12 duodenal ulcer need two to three weeks, if necessary, the drug can be extended to four-five weeks. When esophagitis, gastric ulcer, long-existing erosive gastritis the drug need to drink within 4-8 weeks - that after all this time the sores begin to heal. If the patient, but "Omeprazole" is assigned to other antiulcer drugs, duration of treatment of ulcer 12 duodenal ulcer should be 1 month, reflux esophagitis and gastric ulcers is 2 months.

Because ulcerative lesions of the gastrointestinal tract develops, completely rid of the disease for one course of treatment does not always work. At high risk of recurrent ulcers prevention treatment, it is performed 3-4 times during the calendar year. At low or moderate risk of recurrence, prophylactic treatment is prescribed 2 times per year.

Contraindications, side effects "Omeprazole"



"Omeprazole" is contraindicated in children, women during lactation, in cases of hypersensitivity to the drug components. Renal, hepatic insufficiency, during pregnancy remedy used with caution, under medical supervision.
In case of overdose of the drug develops drowsiness, confusion, arrhythmia, blurred vision, tachycardia, nausea, headache, dryness of the oral mucosa.


"Omeprazole" for reviews can have on the body the following side effects: vomiting, nausea, constipation, diarrhea, flatulence, disturbance of taste, abdominal pain, liver function abnormality, dryness of mouth, hepatitis, increased sweating, blurred vision, pain in muscles, joints.
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