Advice 1: Is down syndrome a hereditary disease

Down syndrome today is the most common genetic disorder. The name of this pathology was named after the English physician John Langdon of Haden down, who in 1866 first scientifically described its features.
Is down syndrome a hereditary disease
Instruction
1
To date, the syndrome is already quite well studied. It's a genetic disorder, which is characterized by the presence of one extra chromosome (i.e., the person 47 chromosomes instead of 46). 21-th pair (a total of 23) of chromosomes represented not two, but three copies. In rare cases, down syndrome can result from translocation of chromosome 21-th pair or mosaicism.
2
From the birth of a baby with down syndrome no one is immune. His appearance has nothing to do with race, gender, parents ' behavior or environmental factors. An average of 1100 children, 1 born with down syndrome. In fact, such children could be more, but in 90% of cases, the woman aborts the pregnancy if prenatal diagnosis confirmed stage this pathology of the fetus. Diagnosis of the syndrome involves the following tests - amniocentesis, chorion biopsy, cordocentesis, which help to answer the question does the future fetus syndrome or not.
3
People with down syndrome differ from healthy next characteristics:
- a broad, flat face with the fold at the inner part of the eye (this is synonymous with the syndrome for a long time was the term "Mongolism");
- small ears, short nose, large tongue and teeth are located in violation;
- reduced muscle tone;
- short fingers, the little finger is often curved;
- delay of mental, physical, and speech development;
- reduced life expectancy.
4
In 91 cases out of 100 down syndrome is not a hereditary disorder. A significant factor increasing the risk of birth of a baby with down syndrome is Newey the age of the mother. After 35-36 years, the risk of conception of such a "special" child dramatically increases several times. In addition, fathers who at the time of fertilization for more than 42 years old can also give birth to a baby with down syndrome.
In rare cases, down Syndrome can be a hereditary disease. This occurs if at least one parent is present translocation.
Men with down syndrome are 100% infertile, and therefore cannot pass their pathology is inherited. Women suffering from down syndrome are quite capable to give birth, but approximately half of the cases their children will be "awarded" with this pathology.
If parents were already conceived a child with down syndrome, the probability of having another child with this problem is 1%.

Advice 2 : How to recognize down syndrome

Down syndrome is the most common genetic disorder, occurring in one out of 700 babies. "Culprit" of deflection is the extra 21st chromosome. Not every woman is ready to raise a child with the syndromeom syndrome, so it's important to recognize it.
How to recognize down syndrome
Instruction
1
The birth of a child with a syndrome down randomly and doesn't depend on the lifestyle of parents and the influence of adverse environmental factors. Doesn't matter the sex of the baby: boys and girls with this genetic disorder are born with equal frequency. The only thing that increases the risk of the birth of the baby, maternal age (over 35 years), however, Ponderosa women have all the chances of a healthy baby.
2
There are many methods to detect syndrome down syndrome during pregnancy. Go ultrasound at 12 weeks. An indirect sign of the deviation is the thickness of the neck area in excess of 2.5-3 mm. in addition, the value and size of the nasal bone in a fetus with a syndrome down it is either absent or has a very small size. In any case, ultrasound can not give 100% answer about the presence or absence of genetic disorders, the detection of specific features of the syndrome of down is necessary to consult genetics and further examination.
3
Pass screening biochemical research. It is most informative on the timing 10-13 (double test) and 16-18 weeks (triple test). A blood test, doctors can calculate the risk of having a child with syndrome of down, however, to give full assurance that the baby will be sick or healthy, it is impossible. When you receive bad results also the necessary consultations genetics and invasive diagnostics.
4
Invasive prenatal diagnosis is able to give a precise answer about the presence or absence of the child syndrome down's, however, the procedure may lead to interruption of pregnancy and therefore is performed only when there is strong evidence (maternal age over 35 years, burdened by genetic anamnesis, presence of abnormalities based on ultrasound or screening tests blood). In the period of 9.5-12 weeks is typically performed a biopsy of the chorion, at 16-20 weeks — amniocentesis (examination of amniotic fluid), after 20-22 weeks cordocentesis (umbilical cord blood study).
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If the deviation in the fetus was not identified for one reason or another, it can be defined by their appearance already in the unborn child. In most cases, a newborn with a syndrome of down has a "flat face", slanted eyes, the brachycephalic (short skull), skin fold on the neck etc If in doubt is a blood test for karyotype.

Advice 3 : Is down syndrome a hereditary disease

Down syndrome today is the most common genetic disorder. The name of this pathology was named after the English physician John Langdon of Haden down, who in 1866 first scientifically described its features.
Is down syndrome a hereditary disease
Instruction
1
To date, the syndrome is already quite well studied. It's a genetic disorder, which is characterized by the presence of one extra chromosome (i.e., the person 47 chromosomes instead of 46). 21-th pair (a total of 23) of chromosomes represented not two, but three copies. In rare cases, down syndrome can result from translocation of chromosome 21-th pair or mosaicism.
2
From the birth of a baby with down syndrome no one is immune. His appearance has nothing to do with race, gender, parents ' behavior or environmental factors. An average of 1100 children, 1 born with down syndrome. In fact, such children could be more, but in 90% of cases, the woman aborts the pregnancy if prenatal diagnosis confirmed stage this pathology of the fetus. Diagnosis of the syndrome involves the following tests - amniocentesis, chorion biopsy, cordocentesis, which help to answer the question does the future fetus syndrome or not.
3
People with down syndrome differ from healthy next characteristics:
- a broad, flat face with the fold at the inner part of the eye (this is synonymous with the syndrome for a long time was the term "Mongolism");
- small ears, short nose, large tongue and teeth are located in violation;
- reduced muscle tone;
- short fingers, the little finger is often curved;
- delay of mental, physical, and speech development;
- reduced life expectancy.
4
In 91 cases out of 100 down syndrome is not a hereditary disorder. A significant factor increasing the risk of birth of a baby with down syndrome is Newey the age of the mother. After 35-36 years, the risk of conception of such a "special" child dramatically increases several times. In addition, fathers who at the time of fertilization for more than 42 years old can also give birth to a baby with down syndrome.
In rare cases, down Syndrome can be a hereditary disease. This occurs if at least one parent is present translocation.
Men with down syndrome are 100% infertile, and therefore cannot pass their pathology is inherited. Women suffering from down syndrome are quite capable to give birth, but approximately half of the cases their children will be "awarded" with this pathology.
If parents were already conceived a child with down syndrome, the probability of having another child with this problem is 1%.
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